Sep. 30, 2024
Purpose: To compare fluorescein angiography and indocyanine green angiography for imaging of choroidal neovascularization located under subretinal hemorrhage, in age-related macular degeneration.
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Methods: In a retrospective study, 30 eyes of 30 consecutive patients with hemorrhagic age-related macular degeneration were evaluated with fluorescein angiography and indocyanine green angiography. In each eye, areas of macular hemorrhage, choroidal neovascularization, and total lesion (hemorrhage plus choroidal neovascularization) were measured, and the choroidal neovascularization was categorized as classic, occult, or mixed on fluorescein angiography, and as hot spot, plaque, or combined lesion on indocyanine green angiography. Results of the two techniques were compared for the ability to identify a laser-treatable lesion.
Results: Fluorescein angiography showed fluorescence in most cases (28, 93.3%). In 23 cases (76.6%), the fluorescence pattern was compatible with occult choroidal neovascularization. Indocyanine green angiography revealed defined patterns of fluorescence in 27 cases (90%): 12 hot spots, seven plaques, and eight combined hot spots and plaques. Twenty lesions (66.6%) detected by indocyanine green angiography were considered eligible for laser therapy. Nine of them (45%) were extrafoveal.
Conclusions: Indocyanine green angiography is beneficial for imaging choroidal neovascularization located under subretinal hemorrhage. Choroidal neovascularization demonstrated on indocyanine green angiography may be considered eligible for laser treatment. Therefore, indocyanine green angiography should be considered in cases of hemorrhagic age-related macular degeneration.
The test lasts for about 10 minutes in the case of the fluoresceinography and, in the case of the indocyanography around 40 minutes. Nevertheless, the total time that the patient spends in the centre from arrival to departure is around 1 hour.
You do not need to fast before the test. You should have breakfast like any other day but not eat excessively.
If you are looking for more details, kindly visit Indocyanine Green Angiography.
It is very important to come to the test with someone else, because your vision will be temporarily blurred. Your pupil will be dilated so you will not be able to drive after the test.
The side effects that pupils may experience from the test are the result of pupils being dilated and may include glare and blurred vision. During the test we can see the flashes and lights that are emitted by the apparatus and on occasions we may experience some nausea or temporary heat. In some exceptional occasions stronger sensations may be experienced.
After the test the patient may continue to experience blurred vision for a few hours as a result of the dilating drops. Some patients may also experience a change in skin colour or the colour of their urine, as the dye is eliminated through the urine.
We have a medical and nursing team who are trained in resuscitation and are available at all times in case of an emergency.
The glare effects last for as long as the effects of the eye drops, which can last for around 4 hours, while the change in urine colour can last for 1 to 3 days, depending on the patient&#;s renal function.
ICR has the best technology on the market. The highly versatile tool that we use can be adapted and focused depending on the patient&#;s illness to obtain detailed images of the internal layers of the eye, as well as combining the angiography with another test that provides lots of information, the optical coherence tomography (OCT).
For more information, please visit Laser Retinal Imaging.
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