Oct. 28, 2024
Butyric acid is a vital fatty acid produced when the good bacteria in the gut break down dietary fibre. It is naturally found in animal fats and vegetable oils, however, the quantity of butyric acid found in food sources is less compared to the amount produced in the gut.
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Butyric acid is known as a short-chain fatty acid (SCFA), which is one among the three most common SCFA&#;s in the gut, along with acetic acid and propionic acid. These saturated fatty acids comprise about 90-95 % of the SCFAs in the gut that is produced when gut-friendly bacteria break down dietary fibre. Butyric acid is well-known to support digestive health, reduce inflammation and lowers the risk of diseases and promote overall health. It holds a significant role in providing colon cells with the needed energy to carry out its normal functions and also regulates blood sugar and cholesterol levels. It goes by other names such as butyrate and butanoic acid.
Butyric acid serves as a chief source of energy for colon cells, which make up the lining of the intestine. While most of the body cells utilise glucose as the main source of energy, the colon cells lining gut chiefly use butyrate, without butyrate these cells are unable to perform normal functions. The short-chain fatty acids offer an oxygen-free environment that supports the growth of gut microbes that controls inflammation and maintain gut cells healthy.
Also Read: Prebiotics: 5 Awesome Foods That Uphold Gut Health-Infographic
Butyrate guards the cells against detrimental substances to keep gut healthy and disease-free. A colon is a storage place of the waster products. Higher levels of butyrate have shown to increase levels of glutathione, an antioxidants made in the system which neutralises free radicals in the gut. This improves the barrier function of the colonocytes and lowers the risk of bowel cancer, inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS).
Regular intake of high fibre diet increases the amount of butyric acid produced in the gut which is well-known to reduce the risk of colon cancer. Studies have proven that butyric acid is a potential to prevent and treat colon cancer by blocking the growth of colorectal tumour cells. Moreover, it also leads to apoptosis that stops the growth of cancer cells completely.
Studies show that butyrate stimulates the secretion of gut hormones such as glucagon &#;like-peptide -1(GLP-1) and peptide YY (PYY).GLP-1 hormones increase insulin secretion and lower the production of glucagon in the pancreas. While the PYY hormones promote the uptake of glucose in muscles and fatty tissue. Thus the presence of butyric acid increases the secretion of gut hormones that regulate type 2 diabetes and control weight
Butyric acid plays a key role in promoting neuroprotective effects that trigger brain and nervous system function. Butyrate targets several pathways linked with the progression of neurodegenerative diseases like Parkinson&#;s, Alzheimer&#;s stroke and autism. A diet abundant in butyric acid is an effective way to improve disease outcomes and uplift overall health.
Generally, most of the butyric acid in the body is made from the gut bacteria. While some amount of butyric acid is also found naturally in food sources which include:
Ghee
Cow&#;s milk
Butter
Sheep&#;s milk
Breast milk
Parmesan cheese
Red meat
Vegetable oils
Sauerkraut
Butter is one of the richest sources of butyric acid. It is also available in the form of dietary supplement as sodium butyrate. However, increasing the intake of dietary fibre can also help to boost butyric acid level in the gut. The gut bacteria chiefly feed on resistant starches which the body can&#;t break down. Some of the good sources of resistant starches, pectin found in many fruits and inulin.
Also Read: Dietary Fibre And Its Role In Preventing Chronic Diseases
Garlic
Onions
Asparagus
Potatoes
Bananas
Apples
Apricots
Carrots
Oat bran
Butyric acid is one of the most beneficial short-chain fatty acids that play a key role in uplifting digestive health, reduces inflammation, protects the brain, manages weight and prevent cancer. The gut bacteria in the body make butyrate from the foods you can&#;t digest, which renders the body with a host of health benefits. Enriching your diet with fibre will help to elevate the butyric acid production by the gut flora.
The content provided here is for informational purposes only. This blog is not intended to substitute for medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider for any questions or concerns you may have regarding a medical condition. Reliance does not endorse or recommend any specific tests, physicians, procedures, opinions, or other information mentioned on the blog.
Used in food, cosmetics and even agriculture. Butyric acid is not only versatile, but also has a range of health benefits.
Also known as butanoic acid, it is a fascinating ingredient that can be just as versatile in your body. It is believed to counteract inflammation or regulate insulin metabolism, for example. What's more, your body produces it on its own, helped by probiotic bacteria.
From this article you will learn:
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Butyric acid, also known as butanoic acid, is a short chain fatty acid ( short chain fatty acids - SCFA) that plays a key role in gut health. It is produced by the bacteria that live in your digestive system.
Wondering how it works? When you eat fibre that is indigestible to your body, it passes into the large intestine. There, probiotic bacteria residing in the colon convert this fibre into butyric acid. This is a perfect example of symbiosis, where both parties benefit - the bacteria have nourishment and you get an essential substance for your health .
Butyric acid is extremely important for your gut. It acts as a kind of fuel for the epithelial cells lining the colon, helping them to maintain a healthy intestinal barrier. This is important because this barrier prevents harmful substances from entering your body .
.As early as the s, studies were conducted that conclusively established butyric acid as a major source of energy for colonocytes, offering hope for its use in the prevention and treatment of gastrointestinal diseases.. .
Katarzyna Grajpermagister of pharmacy
. .What's more, butyric acid has anti-inflammatory properties, which may help to relieve inflammation in the gut. Some studies also suggest that it may help regulate blood sugar levels and improve metabolism. However, these are preliminary and inconclusive conclusions, so should be approached with caution .
So it is worth paying attention to your diet and making sure you are providing your body with enough fibre. By doing so, the probiotic bacteria will be able to produce butyric acid, which will contribute to your gut health.
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Sodium butyrate is the sodium salt of butyric acid, or a derivative of it. The molecules of butyric acid and butyrate are chemically different . However, the properties of the two substances are so similar that their names are often used interchangeably.
In practice, the sodium atom in butyrate makes this butyric acid derivative more stable. It is for this reason that you will most often encounter sodium butyrate in dietary supplements.
Sodium butyrate is the most common name.
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Studies involving people suffering from irritable bowel syndrome confirm that sodium butyrate is ideal for supporting issues related to bacterial flora imbalances (for example, after antibiotic therapy), constipation and diarrhea, inflammation of the intestinal mucosa, or a diet low in fiber.
Premium Sodium Butyrate capsules are made using the innovative DRcaps® technology. This guarantees that the active ingredients in the product are protected from the destructive effects of stomach acids and digestive enzymes. As a result, we can be sure that the beneficial ingredients are released in the small intestine and are fully absorbed by our body.
Premium Sodium Butyrate from Natu Care is 100% tested, and its composition contains only the highest quality raw materials.
Pros and consPros:
Cons:
Take 3 capsules daily at any time of the day, preferably with a meal. Swallow the capsules whole with water.
Premium Sodium Butyrate is intended for adults.
The product should be used under medical supervision.
I've been using the product for 2 weeks. My stomach feels lighter, and my digestion has improved. I recommend it.
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Butyric acid is a key ingredient for the proper functioning of the epithelial cells of the colon, called colonocytes. It provides up to 70% of the energy these cells need to function .
This, however, is not the only function that butyric acid has in our bodies. It is currently the subject of scientific research to understand its potential effects on the immune system and its ability to reduce inflammation. In addition, its properties affecting insulin regulation are also being studied.
Although the exact mechanism of action of butyric acid at the biochemical level is not yet fully understood, there is some evidence to suggest that it may affect various aspects of bodily function. This may include :
Butyric acid may also help to strengthen the protective barrier in the intestines by participating in the production of the mucus that lining them .
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Butyric acid is a well-known ally in the fight against various digestive problems. First and foremost, this metabolite plays a key role in protecting and regenerating the end sections of the digestive system .
It is also an effective solution if you are struggling with problems such as bloating or constipation. Butyric acid aids intestinal peristalsis, which in practice means that it facilitates the bowel movement process.
.The usefulness of butyric acid in infectious diarrhoea has also been clinically confirmed. This is related, among other things, to the mechanism of regulation of water and electrolyte absorption in the cell membrane of colonocytes.. .
Katarzyna Grajpermagister of pharmacy
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. .What's more, butyric acid helps to control gas accumulation in the intestines. As a result, you are able to reduce the unpleasant bloating that can cause discomfort .
It is also worth adding that some studies suggest additional benefits for your body. Some scientific work has shown that butyric acid may contribute to maintaining a healthy body weight, by regulating metabolic processes related to insulin and lipid production .
Do not, however, consider butyric acid (or its derivative, sodium butyrate) as a weight-loss agent. There is still a dispute among scientists about how butyric acid affects our metabolism.
Most studies are in vitro experiments or those involving animals. There are also researchers who point in their work to links between high concentrations of butyrate or butyric acid and metabolic disorders and cardiovascular disease - as you can see, in this case, what's too much is unhealthy .
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Butyric acid has many important functions in your intestines. Not only is it a source of energy for the cells of the colon, but it also supports their regeneration. In addition, it supports the production of mucus, which is an important part of the protective intestinal barrier .
Thanks to this, butyric acid helps to protect your body from harmful substances and pathogens that could enter the bloodstream through this route.
Animal studies suggest that butyric acid may provide relief from irritable bowel syndrome (IBS) symptoms, such as abdominal pain or irregular bowel movements .
A study review indicates that butyric acid derivatives may be helpful in the treatment of colorectal cancer. The results suggest that the ingredient may induce cancer cell death, improve the efficacy of radiotherapy and protect mucosa from degradation that can occur during chemotherapy .
Butyric acid provides energy to healthy cells and at the same time may inhibit the growth of cancerous ones, a phenomenon known as the Warburg effect. Therefore, there is a hypothesis that certain strains probiotics may exhibit anti-cancer effects .
Butyric acid is also used by intestinal cells to produce energy, which increases oxygen consumption by the epithelium. As a result, the presence of butyric acid-producing bacteria helps to maintain an anaerobic environment in the intestines, which further protects against the colonisation of aerobic pathogens such as Salmonella or bacteria E. coli.
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Butyric acid is not only found in your intestines. Some foods - especially milk and milk products (dairy products), for example butter, cream, yoghurt or hard yellow cheeses - also contain small amounts of it. Support for butyric acid synthesis can also be provided by products rich in probiotics and prebiotics.
By increasing the amount of probiotics in your gut, you increase the amount producers of butyric acid. And by eating prebiotic foods, you provide them with the necessary materials for this production.
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Products rich in probiotics
.Products rich in prebiotics (GOS and FOS fibre)*
.* GOS and FOS fibre are oligosaccharides, or complex carbohydrates (fructooligosaccharides and galactooligosaccharides), which do not digest in the stomach but are only fermented in the large intestine - providing food for probiotic bacteria and contributing to butyric acid production.
.Best results will be achieved by using different fibre fractions from three different groups including cereals, vegetables and fruit. Also ensure adequate hydration.. .
Katarzyna Grajpermagister of pharmacy
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Butyric acid is considered safe, but there are situations in which its use must be abandoned.
Do not take butyric acid or its derivatives (butyrate) if :
Despite its benefits, butyric acid can cause some side effects, although this is rather rare. The most common are gastrointestinal problems such as increased bowel function, nausea, abdominal pain and diarrhoea, and changes in appetite .
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Often these symptoms disappear after a few days, but if they are bothersome or worsen, you should stop supplementation and consult your doctor.
The effects of allergic reactions are a different matter. Their symptoms are :
If this occurs, discontinue use of the butyric acid preparation immediately and contact your doctor.
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Note: butyric acid is a really smelly thing. Think twice about whether you want to make it at home (if you live in a block of flats, think about your neighbours too). Another important thing: Do not eat butyric acid obtained this way!
To make butyric acid, all you need to do is leave the butter out of the fridge - until it goes rancid. But to be able to isolate it, you can use this recipe:
Butyric acid occurs naturally in many products, especially butter. You will also find it in other dairy products such as cheese, cream and yoghurt. Furthermore, it is also contained in ghee, a type of clarified butter.
Butyric acid is also produced in the human body - in the gut, as a result of the fermentation of fibre by bacteria. For this reason, eat fibre-rich foods such as fruit, vegetables, nuts, seeds and whole-grain cereal products. This is important because butyric acid has many health benefits. It has anti-inflammatory effects and supports gut health.
. What are the side effects of taking butyric acid? .Taking butyric acid can lead to several side effects. The most common are abdominal pain, bloating, diarrhoea and nausea. For these symptoms, reduce the dose of butyric acid or divide it into several smaller portions throughout the day. This may help to minimise discomfort. Sometimes an allergic reaction may also occur.
. What is the smell of butyric acid? .Butyric acid has an intense, unpleasant odour that is often compared to the smell of... vomit. This is due to the specific chemical structure of this acid, which contains four carbon atoms in its chain. However, in small quantities, it can contribute to the characteristic taste of some foods (especially cheese).
. What is the formula of butyric acid? .The chemical formula of butyric acid is C4H8O2. It is a carboxylic acid that consists of four carbon atoms (C), eight hydrogen atoms (H) and two oxygen atoms (O). Carbon (C) comes first, followed by hydrogen (H) and finally oxygen (O).
This order is important because it indicates the structure of the molecule. Other chemical formulas of butyric acid that you may encounter are C3H7COOH and CH3(CH2)2COOH.
. How much does butyric acid cost? .Dietary supplements containing butyric acid, or more commonly its derivative - sodium butyrate - cost from around £30 to £150. Differences in price may be due to the quality of the raw material itself, the size of the packaging and the additional active ingredients used in the formulation.
. Is butyric acid in medicinal form? .Butyric acid (also in the form of sodium butyrate) is only available in Poland as a dietary supplement. You can find it in health food shops or pharmacies. Only buy products from trusted manufacturers to ensure the best quality and safety.
Butyric acid is important for intestinal health, as it is the main source of energy for intestinal epithelial cells. An example of a product containing butyric acid in the form of sodium butyrate is Panaseus Formula for the Gut.
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